Neurologically, It's much better to be for something than against something. When you're for something positive, you get dopamine and endorphins. Your capillaries open up. You get more blood to the brain. Less wrinkles. Less cortisol. More Melatonin (better sleep). Less hypertension, stroke, coronary disease. Less constipation. Better memory and creativity. And you live longer and better.
When you're against something, you get more cortisol, more adrenallin, more wrinkles, more heart disease, more chance of stroke. And hemorrhoids.
I know how I want to live.